
Helicobacter Pylori is a gram-negative, microaerophilic bacterium that can inhabit different areas of the stomach, especially antral. This leads to a low level inflammation of the stomach and is associated with gastric ulcers and stomach cancer. On the positive, 80% are asymptomatic. Originally named Campyloacter pyloridis, then renamed C. pylori to correct mistakes of Latin grammar. Later he was placed in the genus, Helicobacter. Over 50% of the population has H. pylorus in their gastrointestinal tract. It is more prevalent in developing countries. The infection causes abdominal pain, abdominal pain, heartburn, belching, vomiting, belching, flatulence and nausea. If untreated, the infection may be associated with several serious diseases. It has five main families of foreign protein coat. The outer shell consists of helicobacter phospholipids and lipopolysaccharide. There are a variety of strains and three genomes have been completely consistent. Genome Research H. Pylori, usually trying to understand the pathogenesis of which is the ability of this organism to cause disease. Code CagA gene is associated with the ability to cause ulcers. H. pylori must survive acid clearance in order to colonize the stomach. Movement of the flagella of bacteria through the lumen of the stomach and drill holes in the mucous lining of the stomach. Many bacteria can be found deep in the slime, which is being continuously released. It can also be found on the inner surface of epithelial cells of the stomach. This produces a large number of urease molecules are localized inside and outside the bacteria. Urease splits urea into carbon dioxide and ammonia. Survival depends on the urease of Helicobacter pylori in the stomach. When H. pylori colonizing the stomach leads to chronic gastritis. In many cases, inflammation can lead to gastric ulcers. Type of ulcer of the position of chronic gastritis. Chronic inflammation can eventually lead to atrophy of the gastric mucosa. Western patients with CAG PAI have a strattera 10mg stronger inflammatory response in the stomach and a higher risk of peptic ulcer and gastric cancer. It is possible that H. pylori may contribute to cancer by expanding the production of free radicals in H.pylori and increase the speed of the host cell mutation. It may also promote cancer by increasing the transformed phenotype of a host cell by changes in cellular proteins. Diagnosis by means of dyspeptic phenomena and tests that may indicate helicobacter infection. Doctors use blood antibody tests, antigen tests chair and carbon urea breath tests to detect infection. The most reliable test check endoscopy with biopsy for rapid urease test, histological examination and microbial culture. None of these methods is entirely reliable. Some studies have investigated factors as nutrition in disease. .
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